Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
[18F]BBPA
- Development stage
- Unknown
- Lead developer
- BoomRay Pharmaceuticals
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
[18F]BBPA (also known as BR-02 or [18F]BF3-BPA) is an investigational, unapproved small-molecule radiopharmaceutical and PET tracer. It is a trifluoroborate-derived boronophenylalanine (a bis-boron boramino acid) designed for the positron emission tomography (PET) imaging of primary and metastatic brain tumors, such as gliomas. It acts as a pan-cancer probe, entering cells via the large neutral amino acid transporter type-1 (LAT-1). Because it shares an identical chemical structure with boron carriers used in boron neutron capture therapy (BNCT) (with the only difference being the fluorine isotope), [18F]BBPA serves as a theranostic agent to estimate tumor boron concentration prior to BNCT. It exhibits rapid clearance, low normal-tissue affinity, and a short elimination half-life.
- Other names
- 18F-BBPA18F-BF3-BPA[18F]BF3-BPAbis-boron boramino acidbis-boron boronophenylalaninetrifluoroborate boronophenylalaninetrifluoroborate-derived boronophenylalanine
02
Targets
SLC7A5 (Large neutral amino acid transporter small subunit 1)
Beyond the preview
Go deeper on [18F]BBPA.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on [18F]BBPA.